Paediatric Allergy and Immunology

Overview

What Is Paediatric Allergy and Immunology?

Paediatric allergy and immunology is a medical subspecialty that falls under the larger paediatrics field, focused on children whose immune systems react in unusual or exaggerated ways. Some children have allergies, where the body treats harmless things like pollen or peanuts as a threat. Immune deficiencies, where the immune system does not defend the body properly against infections are present in others. Both situations affect a child's daily life. This includes sleep, school attendance and even growth.

Looking beyond just the sneezing and rashes, a paediatric allergy specialist investigates what is triggering the reaction or why a child keeps catching unusual infections. The immune systems of children are still developing and because of this, the approach to testing, treatment and long-term planning is different. The goal is to let a child live as normally as possible.

Types of Allergic and Immunologic Conditions in Children

Allergic conditions often appear in the first few years of life for children with food allergies being common triggers. Cow's milk, eggs, wheat, soy, peanuts, tree nuts and fish are most likely to cause reactions which range from mild hives to severe, life-threatening anaphylaxis. Hay fever from pollens and perennial allergies from dust mites, pet dander or mould are seasonal respiratory allergies.

Another frequent presentation is often eczema, or atopic dermatitis, preceding food allergies or asthma in what doctors call the "atopic march." Chronic stuffy noses, sneezing and sleep disruption are caused by allergic rhinitis. Some children have allergic conjunctivitis with itchy, watery eyes. Falling under this field as well are drug allergies, insect sting reactions and contact dermatitis from irritants like perfumes or chemicals.

The immunology side is different in nature. Primary immunodeficiency disorders mean a child gets infections that are unusually frequent, severe or caused by bugs that do not trouble other children. These range from selective IgA deficiency, which is often mild, to severe combined immunodeficiency (SCID), where a child lacks functional T cells. Things that all point to an underlying defect in immune function are recurrent pneumonia, persistent thrush, deep skin abscesses or failure to thrive.

Parents often wonder whether a runny nose or a rash needs a specialist. Reactions that keep happening with the same trigger are signs that suggest it is time to see a paediatric allergy specialist. For example, this could be a child who breaks out in hives every time after eating eggs or who starts wheezing when staying at a house with a cat. Medical attention should be sought if any episode such as difficulty breathing, throat tightness or swelling of the lips or tongue after eating or an insect sting, immediately.

Another reason is eczema that cracks, weeps or keeps a child awake despite regular moisturisers and creams. If they follow a seasonal pattern, frequent nasal congestion, chronic cough, or recurrent "colds" that actually turn out to be allergy symptoms should be evaluated. For possible immune deficiency, there are red flags. This includes two or more pneumonias in a year, recurrent deep abscesses, needing intravenous antibiotics to clear common infections or unusual infections like fungal overgrowth in the mouth beyond infancy.

A careful dive looking into patient history is the start. The specialist asks exactly what happens. This looks into how soon after exposure and whether symptoms resolve with antihistamines or avoidance. A food and symptom diary is often very helpful, over two to three weeks. Skin prick testing is the most common allergy test and is when tiny drops of purified allergen extracts are placed on the forearm or back, and a small prick introduces them just under the skin. A raised, red bump, if appearing within 15 minutes, indicates sensitivity. An alternative is also blood tests for specific IgE antibodies to individual allergens. This is particularly useful for children with extensive eczema or those who cannot stop antihistamines.

For delayed reactions that appear 48–72 hours later, patch testing is used. This is especially useful for contact dermatitis. Pulmonary function tests are possible in older children who can cooperate with breathing into a machine. For younger children, the response to medication is often observed clinically. The standard for suspected immune deficiency are a complete blood count with differential, quantitative immunoglobulins (IgG, IgA, IgM, IgE) and antibody response to vaccines. We arrange advanced flow cytometry for lymphocyte subsets or genetic testing when specific disorders are suspected.

  • Food allergies
  • Allergic rhinitis and hay fever
  • Allergic conjunctivitis
  • Atopic dermatitis (eczema)
  • Allergic asthma
  • Acute and chronic urticaria (hives)
  • Anaphylaxis and severe allergic reactions
  • Drug allergies and drug desensitisation
  • Insect venom allergy
  • Primary immunodeficiency disorders
  • Recurrent or unusual infections
  • Eosinophilic oesophagitis and other eosinophilic disorders
  • Hereditary angioedema

Treatment is tailored to the child's age, the specific condition and the family's daily routine at NMC. The first pillar is allergen avoidance. This is balanced however, against over-restriction that might affect nutrition or social development. The team educates families on reading labels, recognising early symptoms of a reaction for food allergies and using emergency medication including adrenaline auto-injectors. Oral food challenges – where a child eats a gradually increasing amount of a suspected allergen under medical supervision – are performed.

Medications include non-sedating antihistamines, nasal corticosteroid sprays and topical steroid or calcineurin inhibitor creams for respiratory allergies and eczema. Asthma is managed using reliever and controller inhalers. Age-appropriate devices like spacers and masks are also used. For dust mite allergy or venom allergy, allergen immunotherapy is offered for severe hay fever, also known as desensitisation. Either as regular injections or as drops/tablets under the tongue, this involves giving gradually increasing doses of the allergen. This helps retrain the immune system to tolerate the trigger.

Treatment may include regular immunoglobulin replacement infusions, antibiotic prophylaxis for primary immunodeficiencies. In severe cases, a referral is made for haematopoietic stem cell transplantation. For severe eczema, biologic therapies such as omalizumab (for allergic asthma) or dupilumab (for severe eczema) are available for children who do not respond to standard treatments.

NMC's paediatric allergy and immunology team consists of consultant paediatricians with additional subspecialty training in allergy and clinical immunology. Supporting them are teams with different expertise. Our paediatric nurses are trained in emergency allergy management, and our dietitians help families navigate food avoidance without nutritional gaps. Respiratory therapists across NMC educate on inhaler technique and lung function testing.

Our specialists take time during every consultation. Explaining test results and demonstrating how to use auto-injectors or inhalers correctly are a standard part of care. Written emergency action plans for schools and nurseries are also offered by our team with every family receiving a clear plan, not just a prescription. Patients can expect the same consistent, practical and compassionate approach to children with allergies and immune problems across every NMC facility in Dubai, Abu Dhabi and the wider UAE.

FAQs

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Frequently Asked Questions

Yes. Most children outgrow milk, egg, wheat and soy allergies by school age. Peanut, tree nut, fish and shellfish allergies persist into adulthood in most cases, but some children do outgrow them. Follow-up testing is done every 12–24 months which helps in determining if an oral challenge is safe.
It is a device that delivers a single fixed dose of adrenaline, medically known as epinephrine, into the thigh muscle. For an anaphylactic reaction, it’s the first-line treatment. For any severe allergic reaction, it’s also used, such as breathing difficulty, throat swelling, persistent dizziness or collapse. If at risk, all families of children are trained on how and when to use it.
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