Movement Disorders

Overview

What are Movement Disorders?

Movement disorders refer to a group of neurological conditions that affect speed, fluency, quality and ease of movement. The brain sends electrical and chemical signals through nerves to the muscles. This tells the muscles when to contract, relax or stay still. When the parts of the brain that control these signals become damaged or start to degenerate, the result can be either a lack of movement or an excess of abnormal, involuntary movements.

Although presenting differently than in adults, movement disorders in children can also occur. In paediatric cases, these are mostly related to cerebral palsy, genetic conditions or acquired brain injuries. For adults, the most recognised neurological movement disorder is Parkinson's disease, but there are many others, including essential tremor, dystonia and Huntington's disease. These conditions tend to be progressive, which means symptoms worsen over time. The right treatment plan can significantly improve quality of life.

Types of Movement Disorders

In clinical settings, Parkinson's disease is the most frequent disease seen. It results from the loss of dopamine-producing cells in a part of the brain called the basal ganglia. Slowness of movement, stiffness, resting tremor and problems with balance and walking are the ways in which symptoms manifest.

Essential tremor is another disorder that causes a rhythmic shaking during activities like writing or holding a cup, usually in the hands. It's often mistaken for Parkinson's, but it is a separate condition.

Dystonia expresses as sustained or repetitive muscle contractions. This leads to twisting movements or abnormal postures. It can affect a single body part, like the neck or an eyelid or be more generalised.

Huntington's disease is an inherited disorder that causes chorea. This is seen as jerky, dance-like movements accompanied by cognitive and psychiatric decline.

Restless legs syndrome creates an irresistible urge to move the legs which often disrupts sleep as it happens in the evening or at night.

Tourette syndrome is a tic disorder and like all other tic disorders produces sudden, repetitive, non-rhythmic movements or vocalisations.

When abnormal movements start to interfere with daily life, a person should see a neurologist. Occasional twitches or jerks are normal, but a persistent tremor in the hands, even at rest, warrants an evaluation. Experiencing difficulty with tasks that were once easy, such as writing, buttoning a shirt or walking without stumbling should be investigated as well.

A change in gait, such as taking smaller steps, dragging a foot or losing arm swing on one side are usually early indicators of Parkinson's disease. Experiences like stiffness in the limbs that does not go away with stretching or a tendency to fall backwards when standing up, also needs assessment.

Parents should seek advice if a child misses developmental milestones like sitting, crawling or walking. Early referral to a specialist can make a significant difference in long-term outcomes if there are repeated, unusual postures or jerking movements that the child cannot control.

A thorough clinical examination marks the beginning of a diagnosis, where a neurologist will observe the patient walk, sit, stand, and perform simple tasks. These include things like reaching for an object or writing. Crucial clues are provided when watching for the pattern of the abnormal movement and details like when it happens and what makes it better or worse.

Although no single test exists for most movement disorders, a diagnosis rests on the history and examination. To rule out other causes, such as a tumour, stroke or structural abnormality, an MRI scan of the brain may be ordered. A dopamine transporter (DaT) scan can help distinguish Parkinson's disease from other tremors in some cases and blood tests may help to exclude metabolic or autoimmune conditions. For suspected genetic cases, genetic testing is available, like Huntington's disease in particular.

  • Parkinson's disease and atypical parkinsonism
  • Essential tremor
  • Dystonia
  • Huntington's disease
  • Restless legs syndrome
  • Tourette syndrome and tic disorders
  • Ataxia and gait disorders
  • Myoclonus
  • Drug-induced movement disorders
  • Movement disorders in children

Treatment is tailored and customised, adapted to the specific condition and the individual's symptoms. The mainstay is medication that replaces or mimics dopamine, such as levodopa for Parkinson's disease. These drugs can dramatically improve mobility. Long-term use however may bring side effects; they therefore require careful dose adjustment.

Medications like beta-blockers or anticonvulsants may help for essential tremor and dystonia. For focal dystonias, such as cervical dystonia (twisted neck) or blepharospasm (forced eye closure), botulinum toxin injections are highly effective.

Deep brain stimulation (DBS) is an option when medication is insufficient. This involves implanting fine electrodes into specific brain regions which in return regulate abnormal signals. DBS remains the most effective modality for Parkinson's disease, essential tremor and dystonia. Physical, occupational and speech therapy are also integral parts of care. They help patients maintain function and independence.

NMC's movement disorder team comprises consultant neurologists who possess advanced training in this complex field and a passion for helping. Working alongside them are specialist nurses, physiotherapists and occupational therapists, all possessing a deep understanding of the specific challenges of these conditions. A thorough assessment and a management plan are offered to each patient that fits their daily life.

All kinds of practical matters are covered during consultations such as going through medication timing, managing side effects, fall prevention and even when to consider advanced therapies like DBS. For families and caretakers, the team provides clear explanations about what to expect as the condition evolves. The same standard of care is available across NMC facilities in Dubai, Abu Dhabi, Sharjah, Ajman, Ras Al Khaimah, and Al Ain in the UAE. Patients, whether they need a new diagnosis, a second opinion or help adjusting an existing treatment plan, can all be assisted.

FAQs

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Frequently Asked Questions

Most cases are not directly inherited, so no. In only about 10-15% of people with Parkinson's, a genetic link is found. The majority of cases are idiopathic, which means the cause is unknown, and age and environmental factors do play a role.
DBS is not a cure. When medications are no longer working well, DBS treats and helps control symptoms. Although many patients experience significant improvement in tremor, stiffness and slowness, the underlying condition does continue to progress slowly.
During a tremor, a person experiences a rhythmic back-and-forth shaking of a body part. A tic is a sudden, quick, repetitive movement or sound. These are often preceded by an urge to perform them. Although tics can be suppressed temporarily, tremors cannot.
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