Dr Reham began her career as a resident from National Cancer Institute, Cairo University, Egypt in 2006 and in 2011, she became a specialist in radiology at National Cancer Institute and a part time radiologist at the Child Cancer Hospital and Al Nakheel Hospital in Cairo, Egypt until 2018. Dr Reham became a lecture at National Cancer Institute, Cairo University where she shared her extensive knowledge with students and spreading cancer awareness. In 2018, she moved to Kuwait and continued her medical practice as a senior registrar at the Kuwait Cancer Control Centre, Kuwait which focused more on female imaging and on oncoradiology. Thereafter she moved back to Egypt and worked as consultant and lecturer at National Cancer Institute, Cairo University in 2021.
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